Faculty

Jing Zhang

Jing ZhangTargeting dysregulated Ras signaling network in oncogenic Ras-associated hematopoietic malignancies

My lab uses genetically engineered mouse model to study the mechanisms of human hematopoietic malignancies. Several of our major focuses are listed below:

  1. To identify and validate additional genetic mutations that cooperate with oncogenic Ras during leukemogenesis
  2. Zhang ResearchTo Study the molecular and signaling mechanisms of how oncogenic Ras regulates hematopoietic stem cell functions in a signaling strength-dependent manner to promote leukemogenesis in different lineages of cells
  3. To conduct preclinical studies in our leukemia models using novel therapeutic approaches developed through our mechanistic studies

 

View publications by Jing Zhang on PubMed