Faculty

Jing Zhang

Jing ZhangTargeting dysregulated Ras signaling network in oncogenic Ras-associated hematopoietic malignancies

My lab uses genetically engineered mouse model to study the mechanisms of human hematopoietic malignancies. Several of our major focuses are listed below:

  1. To discover and validate genetic mutations that cooperate with oncogenic Ras to induce and/or promote leukemogenesis.
  2. Zhang ResearchTo study the molecular and signaling mechanisms of how oncogenic Ras regulates hematopoietic stem cell functions to promote leukemogenesis in different lineages of cells.
  3. To conduct preclinical studies in our leukemia models using novel therapeutic approaches developed through our mechanistic studies.

View publications by Jing Zhang on PubMed